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Dear SPMers: I am uncertain about how to do a conjunction analysis with SPM99 on our fMRI study. I have 12 subjects. The design is as follow Run 1: ADADAD... Run 2: BDBDBD... Run 3: CDCDCD... A, B, and C are different tasks and D are fixation point served as rest condition. I would like to find the common areas activated by A, B, and C relative to D. Is it viable to do a SPM99 conjunction analysis among A-D, B-D, and C-D? If not, what is the best model to do the analysis? I know that the implementation of conjunctions in SPM has changed from SPM96 to SPM99, and the contrasts for SPM99 conjunction analysis need to be orthogonal. I searched the SPM e-mail archives, but could not find a clear answer. I greatly appreciate any suggestion and direction on this issue. Sincerely, Yun Dong _/_/_/_/_/_/_/_/_/_/_/_/_/_/_/_/_/_/_/_/_/_/_/_/ Yun Dong, M.D.,Ph.D. Dept. of Brain Pathophysiology, Human Brain Research Center, Graduate School of Medicine, Kyoto University, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan e-mail: [log in to unmask] Phone: +81-75-751-3603 Fax: +81-75-751-3202 _/_/_/_/_/_/_/_/_/_/_/_/_/_/_/_/_/_/_/_/_/_/_/_/