Karsten & Joseph, > In the CheckReg Option, all images are oriented according to the orientation > of the first selected image. This image is displayed in 'Voxel Space', which > is the orientation without the information's of the .mat file (You can see > the differences, when you change in the 'Display' option from 'World Space' > to 'Voxel Space'). To change the view to mm 'World' space just issue this command after starting checkReg spm_orthviews('Space') -Tom