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UNIVERSITY OF HERTFORDSHIRE STATISTICS GROUP SEMINAR SERIES http://www.herts.ac.uk/business/staff_public/nhspencer_public/seminars Sponsored by Department of Statistics, Economics, Accounting and Management Systems, Business School, University of Hertfordshire. Wednesday 14th November 2001, 2:30pm, room C400, Hatfield campus Martin Owen (GlaxoSmithKline) Title: "The benefits of applying experimental design... and the risks of applying it too late or not at all" Abstract: "The presentation is intended as an overview of how Experimental design has been successfully applied within the Chemistry Development Division at GlaxoSmithKline over the past 12 months to gain process understanding and process confidence. There will be particular emphasis on issues which routinely impact on Manufacturing, such as reducing the cost of goods and increasing the security of supply. Case studies that cover scoping, screening, optimisation and robustness designs will show how Experimental Design is an essential tool for process delivery. Examples will be drawn from * early phase R&D projects * processes transferring from R&D to manufacturing * well-established manufacturing processes The critical issues of timing, six sigma and process registration will be addressed. Despite the obvious benefits of experimental design, the uptake of this statistical approach for chemical process investigation was surprisingly limited until fairly recently. A key driver for increased uptake has been the development of automated experimental equipment which facilitates the rapid collection of quality data. The culture of experimental design is now firmly embedded within Chemistry Development and over the past year was applied to over 90% of the projects undertaken at Stevenage. The obstacles initially faced and strategies to encourage uptake of experimental design will be outlined briefly. This paper will be presented by Martin Owen, a Chemical Development Scientist from GlaxoSmithKline, Stevenage has over six years experience of practical implementation of statistical designs within the Pharmaceutical industry and also designing and implementing robotic technology to perform efficient automated experimental designs." Forthcoming... Wednesday 5th December 2001, 2:30pm, room C400, Hatfield campus Michaela Cottee and Sarah Beecham (University of Hertfordshire) For further information regarding location, parking, etc., please contact Neil Spencer (details below). ****************************************************************** Dr Neil H. Spencer, Senior Lecturer in Statistics, Department of Statistics, Accounting and Management Systems, University of Hertfordshire, Hertford Campus, Mangrove Road, Hertford, SG13 8QF, ENGLAND. Telephone: +44 1707 285529 Fax: +44 1707 285489 E-mail: [log in to unmask] WWW: http://www.herts.ac.uk/business/staff_public/nhspencer_public ******************************************************************