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I'm trying to conduct a Medline search for case-control studies in the Journal of Andrology using software called Knowledge Finder that our hospital provides. When I select case-control from the MeSH thesaurus, it gives me a bunch of studies that are retrospective, and highlights the word "retrospective". Some of these studies are clearly not case-control studies. Under publication types, I can't find an appropriate selection. I could limit my search to randomized controlled trials or clinical trials, but not case-control (or for that matter observational or cohort designs). Why can't I limit my search to just case-control designs? Is this a limitation of the Knowledge Finder software or of the Medline database itself? Or am I just missing something obvious? If it is a limitation of Knowledge Finder, what software should I try to lobby for? Steve Simon, [log in to unmask], Standard Disclaimer. STATS: STeve's Attempt to Teach Statistics. http://www.cmh.edu/stats