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Osmotic demeylination syndromes such as central pontine meylinolysis (CPM) has been described mainly in malnourished chronically hyponatraemic patients in whom active rapid correction to normonatraemia was achieved by hypertonic saline. regards. --- "R.W. Wulkan" <[log in to unmask]> wrote: > This week we had an interesting patient: a man (43 > years) who had > the following results when admitted: > > Na 98 mmol/L > > Osmol 229 mmol/L > Urea 1.8 mmol/L > Cortisol 1.36 umol/L > UrOsmol 145 mosmol/L > > His Sodium rose to 123 mmol/L within 12 hours, which > prompted > me to ask why the correction was made that rapidly. > Apparently the patient did all the correction for > himself. Suffering > from psychogenic polydipsia and submitted to water > restriction he > produced an urine volume of 10 L and thus caused the > quick rise of > the sodium level. No neurologic side effects. > > Raymond Wulkan > ===== Dr. M A Al-Jubouri Consultant Chemical Pathologist Whiston Hospital Prescot Merseyside L35 5DR UK __________________________________________________ Do You Yahoo!? Yahoo! Photos - 35mm Quality Prints, Now Get 15 Free! http://photos.yahoo.com/ %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%