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On the subject of the person who enquired about the anti-sm antibodies. I think I would come down on the side of Raymond Wulkan. The world is a very small place to anyone with a modem, some time and a little common sense. I have full sympathy with clinicians who are facing difficult questions from well-informed patients but I don't think the situation is going to get easier. I sent the lady two websites without giving her a personal opinion on symptoms, they were OMIM and the American Autoimmune Related Diseases Association both of which had useful links. I felt that action was appropriate in the circumstances. She can then search herself and perhaps her GP will be grateful for the information passed back. She was smart and motivated enough to find the ACB mailbase so more power to her elbow. Med vänliga hälsningar/With best regards Gareth Gareth Morgan MPhil MSc FIBMS, Institutionen för Mikrobiologi, Patologi och Immunologi(IMPI), H5, Karolinska Institutet, Avdelningar för biomedicinsk laboratorievetenskap och biomedicinska ämnen, Box 12 773, S 11 296, Stockholm Sverige NB/Obs! Visiting address = Lindhagensgatan 92 Kungsholmen e-mail [log in to unmask] Tel +46 8 728 3734 Fax +46 8 728 3688 'A wise person is certain of few things - a fool of everything' %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%