We have looked at a number of automated methods for testosterone and none of them are able to reach down to the sensitivity required for females and pre-adolescent males or females. We still maintain an RIA to detect low end testosterone values on these patients. Appropriate precision and linearity studies will show that the automated immunoassay systems can not reproducibly determine low testosterone results. Dr. Laurence M. Demers Distinguished Professor of Pathology and Medicine The Pennsylvania State University College of Medicine The M. S. Hershey Medical Center Hershey, PA 17033 Tel # (717) 531-8316 FAX ( 717) 531-5380 , , ("\''/").___..--'''"-._ `9_ 9 ) `-. ( ).`-.__.`) (_Y_.)' ._ ) `._ `. ``-..-' _..`--'_..-_/ /--'_.' .' (il).-'' ((i).' ((!.-' %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%