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Helen Grimes wrote; > Shouldn't aliquoting serum be avoided if at all possible, as > primary tube identification does avoid errors, and enables safe > rechecks etc. Surely current anlaysers are such that the majority > of reequests can be done speedily on a main core biochemistry > analsyer and a main immunoassay analyser, passing the primary > tube from one to the other. Using only one tube for all assays can lead to to some unforseen errors. Where there is an analyte with a very wide range of possible results (eg HCG) there can be appreciable carryover from sample probes. If a sample has been analysed on other instruments before the HCG assay carryover can contaminate the original specimen without an obvious source. Mike Collins Mike Collins MLSO3 Clinical Biochemistry & Immunology The General Infirmary at Leeds, Old Medical School, Thoresby Place Leeds LS1 3EX, UK [log in to unmask] 44 (0) 113 392 2915 http://www.leedsteachinghospitals.com The opinions expressed here are my own. My colleagues and employers may not agree with them.