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This CK-MB result is either CK-BB or one of the two macro-ck's, type 1 or
type 2. This can be identified bt CK- electrophoresis.

Tom Hayes
Clinical Chemistry Department
Belfast City Hospital Trust
Tel. 028 9032 9241 Ext.2615


-----Original Message-----
From: Dr David G Williams [mailto:[log in to unmask]]
Sent: 26 October 2000 14:34
To: [log in to unmask]
Subject: CKMB problem



A recent request for CKMB revealed a total CK of 778 IU/L and a CKMB of 1449

IU/L (both were measured using Roche reagents). Other tests and controls in
the 
batch did not reveal any such anomalies.
I have a vague recollection of this sort of effect possibly being caused by 
binding of the enzyme to an immunoglobulin.

Any other ideas?

Dr D G Williams
FRCPath

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