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Dear Colleagues Sorry about the missing Troponin T level - 3.58 ug/L. The only paper I can find is an old Lancet letter from around 1992, which presumably used the older TropT assay. Levels in dermatomyositis and polymyositis patients averaged 4-5 ug/L. As in this patient, there were no signs of cardiac disease in most of the patients. It was assumed that this was evidence for a more widespread cardiac component to the disease than generally recognised. Given our more recent understanding, is that still the case or does the raised TropT in polymyositis represent the regenerating muscle which has the potential to produce TropT (as in the 1997 clin chem paper). The level in our patient would be unlikely to be clinically silent, in my experience, if it represented cardiac damage post MI. So, with apologies for missing the vital figure !, has anyone any experience of TropT levels in polymyositis and what do they mean ? Trevor -- Trevor Gray Dept. of Clinical Chemistry, Northern General Hospital, Sheffield S5 7AU 0114 271 4309 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%