CENTRE FOR MEDICAL STATISTICS
SEMINAR SERIES on BIOSTATISTICS 1998/99
NO 4: Wednesday, January 27th, 1999 2:30pm
"Inferences about population histories from DNA sequence data"
Professor David Balding
University of Reading
This is an exciting time for those interested in what can be "read from
the genes" about histories of humans and other species. Two key
developments are now coming together: (1) appropriate stochastic models
for the genealogical trees underlying samples of DNA sequences, and (2)
MCMC technology in general, but also specifically for parameter spaces
involving trees. I will review and illustrate these developments.
The bad news is that the underlying reality is so complex that strong
modelling assumptions are required, and even then there is typically
large uncertainty about inferences of interest. However, some
interesting inferences can be made which seem to be reasonably
robust to plausible modelling assumptions.
Seminar Room 2.22
Mathematics Department
MacKay Building
Keele University.
ALL Welcome !
Gilbert
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Prof. Gilbert MacKenzie
Director,
Centre for Medical Statistics
Keele University
Staffordshire ST5 5BG
England
Tel: (01782) 583651
Fax: (01782) 584268
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