ANNOUNCEMENT
^^^^^^^^^^^^^
The Second International Meeting on the Genetic Epidemiology of Complex Traits
Churchill College, Cambridge 
1st, 2nd and 3rd April 2000
^^^^^^^^^^^^^
The meeting will provide:
*a one-day taught introductory course on the genetic epidemiology of
complex diseases, which will cover design and analytical issues. 
*a full two day conference programme with updates from international
speakers aimed at an advanced audience 
*a forum where researchers can present their questions to panels of experts 
*poster presentations 
*an opportunity for informal meetings 

^^^^^^^^^^^^^

PROGRAMME 

**********
Day 1: Saturday 1 April 2000 
INTRODUCTORY COURSE 

09.30 Epidemiological designs for assessing genetic influence
Alex MacGregor - London, UK 
10.45 Molecular biology & analysis methods 
Jerry Lanchbury - London, UK 
11.30 Introduction to statistical modelling in genetics
Pak Sham - London, UK 
12.30 Lunch 
13.30 Linkage analysis
Robert Elston - Cleveland, USA 
14.30 Association Studies
Cathryn Lewis - London, UK 
15.15 Transmission disequilibrium tests
David Allison - New-York, USA 
16.15 Tea & Coffee 
16.30 An introduction to structural modelling
Dorret Boomsma - Amsterdam, Holland 
17.15 Complex traits - Future challenges
Nik Schork - Cleveland, USA 
18.00 End of session 
**********

**********
Day 2: Sunday 2 April 2000 

PART 1 TWIN & FAMILY STUDIES IN GENETIC RESEARCH
CHAIRED BY JAAKKO KAPRIO - HELSINKI, FINLAND 

08.55 The use of twins in genes discovery
Tim Spector - London, UK 
09.15 Founder vs outbred populations for gene discovery - Effects of
linkage disequilibrium
Leonid Kruglyak - Seattle, USA 
09.45 Do placentation issues bias twin studies
David Phillips - Southampton, UK 
10.15 Controversies in twin & family studies
Nick Martin - Brisbane, Australia 
10.30 Tea & Coffee 
**********

**********
PART 2 NOVEL APPROACHES TO QTL ANALYSIS 

10.45 Haseman-Elston revisited 
Robert Elston - Cleveland, USA 
11.15 QTL analysis in families
John Blangero - San Antonio, USA 
11.45 QTL analysis in sib pairs
Mike Neale - Richmond, USA 
12.30 Pharmacogenetics: Hype or reality? 
Roland Wolf - Dundee, UK 
13.15 Lunch & Poster Session
**********

********** 
14.00 Break / Guided Tour of Cambridge 
19.00 Banquet - Pembroke College, Cambridge 
**********

**********
Day 3: Monday 3 April 2000 
ADVANCES IN TDT 

08.30 Overview of TDT
Cathryn Lewis - London, UK 
09.00 Analysis of binary traits via allelic association
John Whittaker - Reading, UK 
09.30 TDT and s-TDT for continuous traits
David Allison - New-York, USA 
10.00 Models to study the interplay between genes and environment
Edwin van den Oord - Amsterdam, Holland 
10.30 Tea & Coffee 
10.45 Developments in discrete trait TDTs
Pak Sham - London, UK 
11.15 Regression methods for s-TDT
Lon Cardon - Oxford, UK 
12.00 Lunch & Poster Session 
**********

**********
DEBATE 1 
13.00 Value of SNP association studies vs linkage studies
For: Nik Schork / Against: Lon Cardon /  Moderator: Jerry Lanchbury 
DEBATE 2 
14.00 Do we need guidelines for significance testing in genetic studies?
For: Pak Sham / Against: Robert Elston / 
Moderator: Leonid Kruglyak 
15.00 Tea & Coffee 
**********

**********
15.15 Type II diabetes
Mark McCarthy - London UK 
15.45 Osteoporosis
Alex MacGregor - London, UK 
16.10 Cardiovascular disease
Harold Snieder - London, UK 
16.30 Obesity
David Allison - New-York, USA 
17.00 Close
********** 


^^^^^^^^^^^^^

The venue will be Churchill College, which provides modern comfortable
conference facilities. Hotel-style accommodation will be available, as well
as student accommodation for those on a more limited budget. 

If they wish, delegates may register only for the introductory course or
the advanced meeting.

^^^^^^^^^^^^^

For registration details contact
Christel Barnetson <mailto:[log in to unmask]>

or write/fax to:

Twin Research and Genetic
Epidemiology Unit, St Thomas'
Hospital, Lambeth Palace Road,
LONDON, SE1 7EHUK 

Fax: 00-44-171-922-8234 

^^^^^^^^^^^^^

For more information visit the conference website:
http://www.twin-research.ac.uk


------------------------------------------
 Alex MacGregor
------------------------------------------
 Twin Research & Genetic Epidemiology Unit        
 St. Thomas' Hospital
 Lambeth Palace Road     
 London  SE1 7EH                    
------------------------------------------
 Tel:   0171-928-9292 ext. 3975 / 6984
 Fax:   0171-922-8234  
 mailto:[log in to unmask]
 http://www.twin-research.ac.uk
------------------------------------------    



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