ANNOUNCEMENT
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The Second International Meeting on the Genetic Epidemiology of Complex Traits
Churchill College, Cambridge
1st, 2nd and 3rd April 2000
^^^^^^^^^^^^^
The meeting will provide:
*a one-day taught introductory course on the genetic epidemiology of
complex diseases, which will cover design and analytical issues.
*a full two day conference programme with updates from international
speakers aimed at an advanced audience
*a forum where researchers can present their questions to panels of experts
*poster presentations
*an opportunity for informal meetings
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PROGRAMME
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Day 1: Saturday 1 April 2000
INTRODUCTORY COURSE
09.30 Epidemiological designs for assessing genetic influence
Alex MacGregor - London, UK
10.45 Molecular biology & analysis methods
Jerry Lanchbury - London, UK
11.30 Introduction to statistical modelling in genetics
Pak Sham - London, UK
12.30 Lunch
13.30 Linkage analysis
Robert Elston - Cleveland, USA
14.30 Association Studies
Cathryn Lewis - London, UK
15.15 Transmission disequilibrium tests
David Allison - New-York, USA
16.15 Tea & Coffee
16.30 An introduction to structural modelling
Dorret Boomsma - Amsterdam, Holland
17.15 Complex traits - Future challenges
Nik Schork - Cleveland, USA
18.00 End of session
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Day 2: Sunday 2 April 2000
PART 1 TWIN & FAMILY STUDIES IN GENETIC RESEARCH
CHAIRED BY JAAKKO KAPRIO - HELSINKI, FINLAND
08.55 The use of twins in genes discovery
Tim Spector - London, UK
09.15 Founder vs outbred populations for gene discovery - Effects of
linkage disequilibrium
Leonid Kruglyak - Seattle, USA
09.45 Do placentation issues bias twin studies
David Phillips - Southampton, UK
10.15 Controversies in twin & family studies
Nick Martin - Brisbane, Australia
10.30 Tea & Coffee
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PART 2 NOVEL APPROACHES TO QTL ANALYSIS
10.45 Haseman-Elston revisited
Robert Elston - Cleveland, USA
11.15 QTL analysis in families
John Blangero - San Antonio, USA
11.45 QTL analysis in sib pairs
Mike Neale - Richmond, USA
12.30 Pharmacogenetics: Hype or reality?
Roland Wolf - Dundee, UK
13.15 Lunch & Poster Session
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14.00 Break / Guided Tour of Cambridge
19.00 Banquet - Pembroke College, Cambridge
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Day 3: Monday 3 April 2000
ADVANCES IN TDT
08.30 Overview of TDT
Cathryn Lewis - London, UK
09.00 Analysis of binary traits via allelic association
John Whittaker - Reading, UK
09.30 TDT and s-TDT for continuous traits
David Allison - New-York, USA
10.00 Models to study the interplay between genes and environment
Edwin van den Oord - Amsterdam, Holland
10.30 Tea & Coffee
10.45 Developments in discrete trait TDTs
Pak Sham - London, UK
11.15 Regression methods for s-TDT
Lon Cardon - Oxford, UK
12.00 Lunch & Poster Session
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DEBATE 1
13.00 Value of SNP association studies vs linkage studies
For: Nik Schork / Against: Lon Cardon / Moderator: Jerry Lanchbury
DEBATE 2
14.00 Do we need guidelines for significance testing in genetic studies?
For: Pak Sham / Against: Robert Elston /
Moderator: Leonid Kruglyak
15.00 Tea & Coffee
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15.15 Type II diabetes
Mark McCarthy - London UK
15.45 Osteoporosis
Alex MacGregor - London, UK
16.10 Cardiovascular disease
Harold Snieder - London, UK
16.30 Obesity
David Allison - New-York, USA
17.00 Close
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^^^^^^^^^^^^^
The venue will be Churchill College, which provides modern comfortable
conference facilities. Hotel-style accommodation will be available, as well
as student accommodation for those on a more limited budget.
If they wish, delegates may register only for the introductory course or
the advanced meeting.
^^^^^^^^^^^^^
For registration details contact
Christel Barnetson <mailto:[log in to unmask]>
or write/fax to:
Twin Research and Genetic
Epidemiology Unit, St Thomas'
Hospital, Lambeth Palace Road,
LONDON, SE1 7EHUK
Fax: 00-44-171-922-8234
^^^^^^^^^^^^^
For more information visit the conference website:
http://www.twin-research.ac.uk
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Alex MacGregor
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Twin Research & Genetic Epidemiology Unit
St. Thomas' Hospital
Lambeth Palace Road
London SE1 7EH
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Tel: 0171-928-9292 ext. 3975 / 6984
Fax: 0171-922-8234
mailto:[log in to unmask]
http://www.twin-research.ac.uk
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