Thiopurine methyltransferase (TPMT) activity is reputed to be an
excellent marker for determining patients at risk of azathioprine
myelotoxicity. Does anyone know where the activity can be measured
and/or the variant alleles determined in the UK?
Dr. Eric S. Kilpatrick
Consultant in Chemical Pathology
Department of Clinical Biochemistry
Hull Royal Infirmary
Anlaby Road
Hull HU3 2JZ
Tel 01482-674312
Fax 01482-674310
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