Dear Paolo,
I'm not sure whether you're using fMRI/PET/SPECT, but there was an
interesting discussion on the list last year about ANCOVA vs scaling that
might be of use to you. Try going to
http://www.mailbase.ac.uk/lists/spm/search.html and searching for 'ancova
scaling'. I also found Andrew's course notes on the GLM and the differences
between ANCOVA & scaling helpful; they're at
http://www.fil.ion.ucl.ac.uk/spm/course/notes97/Ch3.pdf
Best wishes,
Geraint
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