Never seen a case (of Raynaud's) aggravated, excacerbated or triggered by
oestrogen (nor progestagen for that matter)
I have had a couple of lupus (moderate severity, ESR >50) patients with
premature menopause who I have (confessions of a GP) put onto OC (and in one
case additional transdermal oestrogen) without advice from a
'Rheumatohypertensivologist' and she didn't get Raynaud's. One might have
thought she would perhaps, however she had a fluctuating anti-DNA and the
diagnosis may have been that of MCTD rather than SLE.
So that's my primary care Case report series (n=approx 3)
Retrospectively I suspect these SLE patients in fact have subclinical PCO
which probably accounts for their oligomenorrhoea. PCO patients however do
tend to ovulate but less frequently and I must admit to not having checked
FSH/LH in the PCO's with oligo or amenorrhoea. Any endocrinologists out
there ?
Dr Jon Wilcox
General Medicine, Paediatrics and Obstetrics,
Glenfield Medical Centre,
452 Glenfield Road,
Auckland 1310, New Zealand
Phone or Fax +649-444-7656
e-mail [log in to unmask]
-----Original Message-----
From: Graham Balin <[log in to unmask]>
To: [log in to unmask] <[log in to unmask]>
Date: Wednesday, November 04, 1998 09:39
Subject: Raynaud's and HRT
>To get away from SAOL's and sexual innuendo and back to some clinical
>stuff...
>Anyone know if any proven links between oestrogen sorry estrogen and
>Raynaud's? Does HRT increase the chance of it being a problem into later
>life? If it is aproblem, should HRT be discontinued?
>
>Cheerio,
>
>Graham
>
>ps SAOL's and SI's welcome
>
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