allan harris wrote:
>
> " The half life of carbon monoxide bound
> to mitochondrial cytochromes may well be much longer than
> that of carboxyhaemoglobin and hyperbaric oxygen has been
> suggested as being important in attacking this binding site."
>
> So maybe there is a role for late hyperbaric O2?
>
>
AFAIK the detrimental effects of CO arise from the preferential
displacement of O2 by CO on the heme molecule forming carboxyhemoglobin.
I have no idea of the clinical significance of CO binding to
mitochondrial cytochromes (probably demonstrating my abysmal ignorance
on the subject...) or the role of O2 in reversing it or what the
dissociation curve would look like or the half life would be - all
things to consider before shelling out 1500 UKP per session.
In any case, as Jel mentioned, the life of the RBC = 120 days.
After a couple courses in diving medicine I do have an appreciation of
hyperbaric medicine in numerous applications. Dubious about this one...
Phil Dunlap, GP
4 Bailey Hill Road
Natick, MA, 01760, USA
[log in to unmask]
(508) 650-9097 - voice
(508) 650-9152 - fax
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