Val Southgate wrote:
>
> At 01:34 AM 1/14/98 -0000, Adrian Midgley wrote:
> >[log in to unmask],Net wrote at 23:12 on 13/01/98
> >about "Re: Nifedipine ?link with Stroke /Ca":
> >-----------------------------
> >>abayomi.mcewen wrote:
> >>> Patient had seen TV programme which patient said linked use of
> >>> Nifedipine with stroke and/or cancer. Did any of you see it? What did
> >>> it really really say?
> >>> (...)
> >
> >The suggestion was that there had been an increased
> >incidence of cancers in Nifedipine users.
> >
> >The putative mechanism was that calcium channel blockade
> >might inhibit the programmed autodestruction which cells
> >demonstrate and which is thought to be one of the
> >protections against multiplication of a cell which has
> >turned cancerous. Apoptosis is it?
>
> >this hypothesis is a bit difficult to credit. the assumption that the
> l-channel regulate calcium leels in cell types that precipitate the
> apparent increase in malignancy is invalid. basically, the channel is
> present on excitable cells like muscles/nerves, where malignancy is rare.
> ironic that hypertension itself is a significant risk factor for cancer.
>
> >Tenous, very tenous, but no doubt the Apricot fancying
> >godfreaks will believe it.
> >--- OffRoad 1.9r registered to Adrian Midgley
> >
> >
Adrian
Getting useful relevant info like this really warms the cockles of my
heart and keeps me attached to GP-UK
Greeting
Yomi
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