On Tue, 6 Aug 96 15:17 BST-1, David Sydenham wrote:
>In-Reply-To: <[log in to unmask]>
>The strange thing about trials of the oral anti herpes Rx's is that they
>seemed to show little benefit, however experience in practice ( a small
>scale trial with all its problems) does seem to show marked reduction in
>the degree of severity of the illness.
>
Wishful thinking or placebo effect perhaps ? :-)
Of course many of the trials have been badly designed or too small, so
may have failed to show a small, but real benefit (see Bandolier's
article on acyclovir for Zoster, which is available on the WWW).
Considering how much the drug companies charge for these drugs to
cover their "development costs" you would think that they could have
funded some decent large studies to settle the issue - but maybe they
don't want to prove exactly how little effect their products really
have!
Dr David Evans
Cardiff
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