At 21:43 07/10/1996 +1300, Jon wrote:
>I am now confused. I am totally unaware of any documented (proven) risk
>associated with statin use.
>Perhaps someone can enlighten me.
>There is most certainly risk with the fibrates.
>Statins are statins and fibrates are fibrates.
Apparently the 4S trial turned up one patient (6000 treatment years?) who
suffered severe muscle pains with raised CPK and had to withdraw. There is
no need to monitor LFTs and CPK on this evidence, but I bet the data sheet
will not be amended because of Gross et al:-( If a patient suffers
*widespread* muscles pains on a statin, stop the drug and measure CPK.
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Dr David J Plews
email: [log in to unmask]
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