Hi SPM members
I’m trying to use a multiple regression model in CAT12. My main purpose is to check whether there are associations (positive/negative) between cortical thickness measures and cognitive scores. At first, I entered the cognitive scores as covariates in the regression models, but now I’m interested in controlling for the effects of age (enter age as a nuisance variable).
After some research in the SPM Archives concerning this matter, I have set up the model as follows:
(1) Tested for the positive and negative age*cognitive_scores interactions; saved the map; excluded the significant areas from the next step
(2) Tested for the effect of cognitive scores (-1 and 1); saved the map.
Can you please check if I have done it correctly, please?
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