Dear Arian,
Of course, CAT12 can examine white matter (WM). However, keep in mind that there are more sensitive methods for WM, such as DTI, and the sensitivity for WM may be lower compared to grey matter. This is because white matter regions are often quite homogeneous in T1-weighted images, making it more difficult to find differences.
However, if you do find something, all is fine, but if you do not, it may simply be due to the lower sensitivity.
Best,
Christian
On Wed, 3 May 2023 21:37:46 -0400, Arian Klows <[log in to unmask]> wrote:
>Hi folks,
>
>Can we use CAT12 for white matter volume analysis?
> It’s so popular with gray matter analysis. Can we still use it for white
>matter volume analysis in cases where DTI couldn’t be acquired?
>
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