Dear SPM experts,
I work on a longitudinal VBM analysis consisting of 3 groups (2 different patient groups and 1 healthy control group) with time point 1 and time point 2. With this dataset, I would like to look at the longitudinal grey matter volume differences between three groups (changes from baseline to follow-up). In addition, I would like to do a cross-sectional analysis between the 3 groups with time point 1 and time point 2 separately. Could you please suggest how I can apply flexible factorial design (or an alternative statistical model) to construct a design and contrast matrix for these two different types of analysis.
thanks,
kind regards,
Varun
|