Dear Sherri,
if CAT12 is so robust, you may not need to change any parameters. However, if the image quality of your data varies, you should check the sample homogeneity and look at the distribution of the image quality parameters. It may be helpful (and sometimes necessary) to remove low image quality data from your analysis.
Best,
Christian
On Fri, 18 Mar 2022 03:04:49 +0000, Sherri Lynn Livengood <[log in to unmask]> wrote:
>Hello,
>
>We are running CAT12 VBM on a group of TBI subjects. We're pretty new to this, so I was hoping someone could suggest some ways to optimize the pipeline or parameters for:
>
> 1) severely damaged brains (the segmentations look surprisingly great tho with a default pipeline)
> 2) quantifying healthy vs unhealthy white matter volume (e.g., hypointensities or other indicators)
>
>Note: These are often pretty poor quality T1s due to motion artifact, but even then CAT12 is shockingly robust.
>
>Thanks for any suggestions or pointers to papers.
>Sherri
>
>Sherri Lynn Livengood, PhD
>Auditory Neuroscientist, Hines VA
>Northwestern's Dept. Physical Medicine & Rehabilitation
>Ph: 206-678-7569 | [log in to unmask]<mailto:[log in to unmask]>
>
>FEINBERG SCHOOL of MEDICINE
>150 Years of Advancing Science, Improving Health
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