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Subject:

[bims-librar] 2020-06-07, eighteen selections

From:

Thomas Krichel <[log in to unmask]>

Reply-To:

Thomas Krichel <[log in to unmask]>

Date:

Sun, 7 Jun 2020 01:55:30 +0000

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bims-librar       Biomed News on Biomedical librarianship
─────────────────────────────┐
Issue of 2020‒06‒07          │ 
eighteen papers selected by  │
Thomas Krichel (Open Library │
 Society)                    │
 http://e.biomed.news/librar │
                             │
                             │
                             └──────────────────────────────────────────────────
────────────────────────────────────────────────────────────────────────────────

 1. Identification of the Best Semantic Expansion to Query PubMed Through 
     Automatic Performance Assessment of Four Search Strategies on All Medical 
     Subject Heading Descriptors: Comparative Study.
 2. Systematic mixed studies reviews: leveraging the literature to answer 
     complex questions through the integration of quantitative and qualitative 
     evidence.
 3. Citizen Science im Kaiserreich. Die Systemstelle „Wertlose 
     Einsendungen aus der Bevölkerung“ im Archiv der Berlin‐Brandenburgischen 
     Akademie der Wissenschaften.
 4. Readability of web-based sources about induced abortion: a 
     cross-sectional study.
 5. Quality and Readability of Online Health Information for Acral 
     Lentiginous Melanoma.
 6. COVID-19-Related Information Sources and the Relationship With 
     Confidence in People Coping with COVID-19: Facebook Survey Study in 
     Taiwan.
 7. Evaluation of Spanish Language Proficiency and Resources Available in 
     Academic Pediatric Orthopaedic Centers.
 8. Use of the Internet by pregnant women to seek information about 
     pregnancy and childbirth.
 9. YouTube™ as a source of information for Candida auris infection: a 
     systematic review.
10. Googling fibroids: A critical appraisal of information available on 
     the internet.
11. Assessment of Online Sites Reliability, Accountability, Readability, 
     Accessibility and Translation for Intravitreal Injections.
12. How adolescent patients search for and appraise online health 
     information: A pilot study.
13. Use and importance of different information sources among patients 
     with rare diseases and their relatives over time: a qualitative study.
14. Developing a Search Engine for Precision Medicine.
15. BRret: Retrieval of Brain Research Related Literature.
16. Chemical Entity Recognition for MEDLINE Indexing.
17. Database combinations to retrieve systematic reviews in overviews of 
     reviews: a methodological study.
18. Text Snippets to Corroborate Medical Relations: An Unsupervised 
     Approach using a Knowledge Graph and Embeddings.

────────────────────────────────────────────────────────────────────────────────

                                      JMIR Med Inform. 2020 Jun 04. 8(6): e12799
 1. Identification of the Best Semantic Expansion to Query PubMed Through 
     Automatic Performance Assessment of Four Search Strategies on All Medical 
     Subject Heading Descriptors: Comparative Study.
   Massonnaud CR, Kerdelhué G, Grosjean J, Lelong R, Griffon N, Darmoni SJ
  BACKGROUND: With the continuous expansion of available biomedical data, 
  efficient and effective information retrieval has become of utmost 
  importance. Semantic expansion of queries using synonyms may improve 
  information retrieval.
   OBJECTIVE: The aim of this study was to automatically construct and evaluate 
  expanded PubMed queries of the form "preferred term"[MH] OR "preferred 
  term"[TIAB] OR "synonym 1"[TIAB] OR "synonym 2"[TIAB] OR …, for each of the 
  28,313 Medical Subject Heading (MeSH) descriptors, by using different 
  semantic expansion strategies. We sought to propose an innovative method 
  that could automatically evaluate these strategies, based on the three main 
  metrics used in information science (precision, recall, and F-measure).
   METHODS: Three semantic expansion strategies were assessed. They differed by 
  the synonyms used to build the queries as follows: MeSH synonyms, Unified 
  Medical Language System (UMLS) mappings, and custom mappings (Catalogue et 
  Index des Sites Médicaux de langue Française [CISMeF]). The precision, 
  recall, and F-measure metrics were automatically computed for the three 
  strategies and for the standard automatic term mapping (ATM) of PubMed. The 
  method to automatically compute the metrics involved computing the number of 
  all relevant citations (A), using National Library of Medicine indexing as 
  the gold standard ("preferred term"[MH]), the number of citations retrieved 
  by the added terms ("synonym 1"[TIAB] OR "synonym 2"[TIAB] OR …) (B), and 
  the number of relevant citations retrieved by the added terms (combining the 
  previous two queries with an "AND" operator) (C). It was possible to 
  programmatically compute the metrics for each strategy using each of the 
  28,313 MeSH descriptors as a "preferred term," corresponding to 239,724 
  different queries built and sent to the PubMed application program 
  interface. The four search strategies were ranked and compared for each 
  metric.
   RESULTS: ATM had the worst performance for all three metrics among the four 
  strategies. The MeSH strategy had the best mean precision (51%, SD 23%). The 
  UMLS strategy had the best recall and F-measure (41%, SD 31% and 36%, SD 
  24%, respectively). CISMeF had the second best recall and F-measure (40%, SD 
  31% and 35%, SD 24%, respectively). However, considering a cutoff of 5%, 
  CISMeF had better precision than UMLS for 1180 descriptors, better recall 
  for 793 descriptors, and better F-measure for 678 descriptors.
   CONCLUSIONS: This study highlights the importance of using semantic 
  expansion strategies to improve information retrieval. However, the 
  performances of a given strategy, relatively to another, varied greatly 
  depending on the MeSH descriptor. These results confirm there is no ideal 
  search strategy for all descriptors. Different semantic expansions should be 
  used depending on the descriptor and the user's objectives. Thus, we 
  developed an interface that allows users to input a descriptor and then 
  proposes the best semantic expansion to maximize the three main metrics 
  (precision, recall, and F-measure).
   Keywords: MEDLINE; Medical Subject Headings; PubMed; bibliographic 
    database; information retrieval; literature search; precision; recall; 
    search strategy; thesaurus
  DOI: https://doi.org/10.2196/12799
  URL: http://pubmed.ncbi.nlm.nih.gov/32496201

                                               Int J Public Health. 2020 Jun 03.
 2. Systematic mixed studies reviews: leveraging the literature to answer 
     complex questions through the integration of quantitative and qualitative 
     evidence.
   Cerigo H, Quesnel-Vallée A
  DOI: https://doi.org/10.1007/s00038-020-01386-3
  URL: http://pubmed.ncbi.nlm.nih.gov/32494870

                                               Ber Wiss. 2018 Dec;41(4): 383-386
 3. Citizen Science im Kaiserreich. Die Systemstelle „Wertlose 
     Einsendungen aus der Bevölkerung“ im Archiv der Berlin‐Brandenburgischen 
     Akademie der Wissenschaften.
   Krajewski M
   Keywords: Archiv; Archivpraktiken; Citizen Science; Einstein; Fermat'sche 
    Vermutung; Fermats Last Theorem; Gutachten; Populärwissenschaft; archival 
    practices; archives; review; scientific ecognition; vernacular science; 
    wissenschaftliche Anerkennung
  DOI: https://doi.org/10.1002/bewi.201801917
  URL: http://pubmed.ncbi.nlm.nih.gov/32495428

                               BMC Med Inform Decis Mak. 2020 Jun 05. 20(1): 102
 4. Readability of web-based sources about induced abortion: a 
     cross-sectional study.
   Georgsson S, Carlsson T
  BACKGROUND: High-quality information is essential if clients who request an 
  abortion are to reach informed decisions and feel prepared for the 
  procedure, but little is known concerning the readability of web-based 
  sources containing such material. The aim was to investigate the readability 
  of web-based information about induced abortion.
   METHODS: The search engine Google was used to identify web pages about 
  induced abortion, written in the English language. A total of 240 hits were 
  screened and 236 web pages fulfilled the inclusion criteria. After 
  correcting for duplicate hits, 185 web pages were included. The readability 
  of the text-based content of each web page was determined with Flesch 
  Kincaid Grade Level, Gunning Fog Index, Coleman-Liau Index, Simple Measure 
  of Gobbledygook, and Flesch Reading Ease. Data were analyzed with 
  descriptive statistics, Pearson's correlation coefficient and Kruskal-Wallis 
  with Dunn's test as post hoc analysis.
   RESULTS: Across all grade level measures, a small minority of the web pages 
  had a readability corresponding to elementary school (n < 3, 1%), while the 
  majority had readability corresponding to senior high school or above 
  (n > 153, 65%). The means of the grade level measures ranged between 10.5 
  and 13.1, and the mean Flesch Reading Ease score was 45.3 (SD 13.6). Only 
  weak correlations (rho < 0.2) were found between the readability measures 
  and search rank in the hit lists. Consistently, web pages affiliated with 
  health care had the least difficult readability and those affiliated with 
  scientific sources had the most difficult readability.
   CONCLUSIONS: Overall, web-based information about induced abortions has 
  difficult readability. Incentives are needed to improve the readability of 
  these texts and ensure that clients encounter understandable information so 
  that they may reach informed decisions and feel adequately prepared when 
  requesting an abortion.
   Keywords: Consumer health information; Induced abortion; Quality; 
    Readability; World wide web
  DOI: https://doi.org/10.1186/s12911-020-01132-y
  URL: http://pubmed.ncbi.nlm.nih.gov/32503524

                                                     Dermatol Surg. 2020 May 29.
 5. Quality and Readability of Online Health Information for Acral 
     Lentiginous Melanoma.
   Yu Z, Dee EC, Nambudiri VE, Ogbechie-Godec OA, Jakus J, Siegel DM
  DOI: https://doi.org/10.1097/DSS.0000000000002457
  URL: http://pubmed.ncbi.nlm.nih.gov/32483094

                                  J Med Internet Res. 2020 Jun 05. 22(6): e20021
 6. COVID-19-Related Information Sources and the Relationship With 
     Confidence in People Coping with COVID-19: Facebook Survey Study in 
     Taiwan.
   Wang PW, Lu WH, Ko NY, Chen YL, Li DJ, Chang YP, Yen CF
  BACKGROUND: People obtain information on the coronavirus disease (COVID-19) 
  from the internet and other sources. Understanding the factors related to 
  such information sources aids health professionals in educating individuals.
   OBJECTIVE: This study used data collected from the online survey study on 
  COVID-19 in Taiwan to examine what major COVID-19 information sources are 
  available and which sources are significantly related to the self-confidence 
  of people in coping with COVID-19 in Taiwan.
   METHODS: A total of 1904 participants (1270 non-health-care workers and 634 
  health care workers) were recruited from the Facebook advertisement. Their 
  major sources of information about COVID-19, the relationships between the 
  sources and demographic factors, and the relationships between the sources 
  and the self-confidence in coping with COVID-19 were surveyed.
   RESULTS: Most Taiwanese people relied on the internet for COVID-19 
  information. Many respondents also used a variety of sources of information 
  on COVID-19; such variety was associated with sex, age, and the level of 
  worry toward COVID-19, as well as if one was a health care worker. For 
  health care workers, the use of formal lessons as an information source was 
  significantly associated with better self-confidence in coping with 
  COVID-19. The significant association between receiving information from 
  more sources and greater self-confidence was found only in health care 
  workers but not in non-health-care workers.
   CONCLUSIONS: Medical professionals should consider subgroups of the 
  population when establishing various means to deliver information on 
  COVID-19.
   Keywords: COVID-19; Facebook; confidence; coping; information; internet; 
    mental health; online health information; social media; survey
  DOI: https://doi.org/10.2196/20021
  URL: http://pubmed.ncbi.nlm.nih.gov/32490839

                                       J Pediatr Orthop. 2020 Jul;40(6): 310-313
 7. Evaluation of Spanish Language Proficiency and Resources Available in 
     Academic Pediatric Orthopaedic Centers.
   Sobel AD, Ramirez JM, Walsh DF, Defroda SF, Cruz AI
  INTRODUCTION: Given the rapidly increasing population of Spanish-speaking 
  patients in the United States, medical providers must have the capability to 
  effectively communicate both with pediatric patients and their caregivers. 
  The purpose of this study was to query the Spanish language proficiency of 
  pediatric orthopaedic surgeons, assess the educational resources available 
  to Spanish-speaking patients and their families, and identify the barriers 
  to care at academic pediatric orthopaedic centers.
   METHODS: The Web sites of medical centers within the United States that have 
  pediatric orthopaedic surgery fellowships recognized by the Pediatric 
  Orthopaedic Society of North America (POSNA) were accessed. Web sites were 
  investigated for a health library as well as the availability of interpreter 
  services. Profiles of attending surgeons within each Pediatric Orthopaedic 
  Department were evaluated for evidence of Spanish proficiency as well as 
  educational qualifications. Centers were contacted by phone to determine if 
  the resources and physicians who could converse in Spanish were different 
  than what was readily available online and if automated instructions in 
  Spanish or a person who could converse in Spanish were available.
   RESULTS: Forty-six centers with 44 fellowship programs were identified. The 
  profiles of 12 of 334 (3.6%) surgeons who completed pediatric orthopaedic 
  fellowships indicated Spanish proficiency. Seventeen physicians (5.1%) were 
  identified as proficient in Spanish after phone calls. Thirty-eight 
  pediatric orthopaedic centers (82.6%) noted interpreter service availability 
  online, although services varied from around-the-clock availability of live 
  interpreters to interpreter phones. When contacted by phone, 45 of 46 
  centers (97.8%) confirmed the availability of any interpreter service for 
  both inpatient and outpatient settings. Sixteen centers (34.8%) had online 
  information on orthopaedic conditions or surgical care translated into 
  Spanish. Twenty centers (43.5%) did not have automated phone messages in 
  Spanish or live operators that spoke Spanish.
   CONCLUSIONS: There is a scarcity of surgical providers in pediatric 
  orthopaedic centers proficient in Spanish, demonstrating a large discrepancy 
  with the growing Hispanic population. Interpreter services are widely 
  available, although there is variability in the services provided. 
  Considerable barriers exist to Spanish-speaking patients who attempt to 
  access care by phone or online.
  DOI: https://doi.org/10.1097/BPO.0000000000001466
  URL: http://pubmed.ncbi.nlm.nih.gov/32501928

                                       Inform Health Soc Care. 2020 Jun 02. 1-11
 8. Use of the Internet by pregnant women to seek information about 
     pregnancy and childbirth.
   Ahmadian L, Khajouei R, Kamali S, Mirzaee M
  Pregnant women get information about pregnancy andchild-birth from many 
  sources, including the Internet. There is alack of evidence about the extent 
  to which pregnant women usethis source. This study aimed to investigate the 
  use of the Internetby pregnant women to search for information about 
  pregnancyand childbirth. This study was conducted in Kerman, Iran. 
  Threehundred eighty-five pregnant women waiting for their appointmentswith 
  obstetricians/gynecologists participated in the survey byfilling out a 
  questionnaire. The most common searched topicswere nutrition in pregnancy 
  (81%), fetal development (67%), andcomplications of pregnancy (49%). The 
  most popular sources ofinformation were physicians (61%), the Internet 
  (51%), and printedsources (41%), respectively. More than half of the 
  participantsdid not share the retrieved information from the Internet with 
  theirhealth professionals. After being examined by a physician, 43% ofthe 
  participants searched the Internet about the discussed topic.Beside 
  physicians, the Internet is the second common source ofpregnancy and 
  childbirth information for Iranian pregnant women.Future studies are needed 
  to analyze the quality and accuracy ofonline pregnancy and childbirth 
  information.
   Keywords: Pregnancy; childbirth; information; internet; online; pregnant 
    woman; world Wide Web
  DOI: https://doi.org/10.1080/17538157.2020.1769106
  URL: http://pubmed.ncbi.nlm.nih.gov/32484715

                                      BMC Public Health. 2020 Jun 01. 20(1): 832
 9. YouTube™ as a source of information for Candida auris infection: a 
     systematic review.
   Huang J, Zhang S, Xiao Q, Cao Y, Li B
  BACKGROUND: Candida auris is a novel Candida species, and has emerged 
  globally as a multidrug-resistant health care-associated fungal pathogen. 
  YouTube™ (http://www.youtube.com) as the largest free video-sharing website 
  is increasingly used to search health information. Thus, the aim of this 
  study was to evaluate the content, reliability and quality of YouTube™ 
  videos regarding Candida auris infection, and to identify whether it is a 
  useful resource for people.
   METHODS: The YouTube™ was used to search systematically for videos using the 
  keywords: "Candida auris infection" and "Candida auris". Strict inclusion 
  and exclusion criteria were used to select the videos. The videos were 
  reviewed and scored by two independent reviewers and recorded the "title", 
  "length", "views", "comments", "dislike", "like", "posted days" and 
  "category of videos". The videos were categorized as "poor", "good" and 
  "excellent" by the score. The DISCERN tool was used to assess the 
  reliability of the YouTube™ videos.
   RESULTS: Seventy-six videos were included in final analysis in our study. 
  Most videos (59.2%, 55/76) had better quality. There were no statistically 
  significant differences between groups in respect of the number of likes, 
  dislikes, views, comments, percentage positivity, likebility, view rate and 
  viewers' interaction. Length and posted days were significantly associated 
  with the classification. The videos were categorized as "educational video", 
  "new report", "personal experience and blog entertainment" and "interview". 
  Significant differences were found in the source of videos and the 
  characteristics of the individuals appearing in a video between the groups.
   CONCLUSION: YouTube™ has striking potential to be an effective user-friendly 
  learning interface for people to obtain information of Candida auris 
  infection.
   Keywords: Candida auris; Infection; Internet; Reliability; YouTube™
  DOI: https://doi.org/10.1186/s12889-020-08731-4
  URL: http://pubmed.ncbi.nlm.nih.gov/32487232

     Eur J Obstet Gynecol Reprod Biol. 2020 Apr 18. pii: S0301-2115(20)30172-X. 
10. Googling fibroids: A critical appraisal of information available on 
     the internet.
   Hirsch M, Wojtaszewska A, Saridogan E, Mavrelos D, Barker C, Duffy JMN
  OBJECTIVE: We aim to evaluate the accuracy, quality, and readability of 
  online patient information concerning fibroids.
   STUDY DESIGN: We searched the most popular Internet search engine: 
  Google.com. We developed a search strategy in consultation with patients 
  with fibroids, to identify relevant websites. Two independent authors 
  screened the search results. Websites were evaluated using validated 
  instruments across three domains, including assessments of: [1] quality 
  (DISCERN instrument; range 0-85); [2] readability (Flesch-Kincaid 
  instrument; range 0-100); and [3] accuracy. Accuracy was assessed using 
  evidence-based statements. We summarised this data narratively including the 
  use of figures and tables.
   RESULTS: We identified 750 websites, of which 48 were included. Over a third 
  of websites did not attribute authorship and almost half the included 
  websites did not report the sources of information or academic references. 
  No website provided written patient information in line with recommendations 
  from the American Medical Association. A minority (18%) of websites were 
  assessed as high quality. Twelve webpages provided only accurate statements. 
  Available information was, in general, skewed towards the surgical 
  management of fibroids. No website scored highly across all three domains.
   CONCLUSION: In the unlikely event that a website reports high quality and 
  accurate health information, it is typically challenging for a lay audience 
  to comprehend. Healthcare professionals and the wider community, should 
  inform women with fibroids of the risk of outdated, inaccurate, or even 
  dangerous information online. The implementation of an Information Standard 
  certification will incentivise providers of online information to establish 
  and adhere to codes of conduct. VIDEO ABSTRACT.
   Keywords: Accuracy; Fibroids; Online information; Patients; Quality; 
    Readability
  DOI: https://doi.org/10.1016/j.ejogrb.2020.04.004
  URL: http://pubmed.ncbi.nlm.nih.gov/32473505

                    Ophthalmol Retina. 2020 Jun 01. pii: S2468-6530(20)30215-3. 
11. Assessment of Online Sites Reliability, Accountability, Readability, 
     Accessibility and Translation for Intravitreal Injections.
   Rayess N, Li AS, Do DV, Rahimy E
  PURPOSE: Patients increasingly use the internet to access health-related 
  information to further understand their treatments and conditions. This 
  study compares the quality, accountability, readability, accessibility and 
  presence of translation between private and academic online source material 
  available to the public regarding intravitreal injections.
   DESIGN: Cross-sectional analysis PARTICIPANTS: Top 20 websites on a Google 
  search for the terms 'eye injections', 'intravitreal injections' and 
  'anti-VEGF injections'.
   METHODS: Websites were classified as private or academic. Quality and 
  accountability were assessed using the internationally recognized DISCERN 
  criteria and the Health on the Net (HONcode). All 20 sites were 
  independently graded by 2 retinal physicians and differences were 
  adjudicated by a third experienced retinal physician. Readability was 
  evaluated using an online tool that provides a consensus readability grade 
  level. The presence of and languages available for translation were 
  recorded. The top 5 ranked websites' content quality, accountability and 
  readability was also compared with the other 15 websites.
   MAIN OUTCOME MEASURES: Primary outcome measure is comparing the DISCERN and 
  HONcode quality and accountability scores between academic and private 
  websites. Secondary outcome measures include evaluating readability, 
  accessibility and presence of translation (in particular, Spanish).
   RESULTS: Eleven academic and 9 private websites were included. The overall 
  mean score using DISCERN criteria for the academic websites (3.11±0.46) was 
  significantly higher than that of private websites (2.23±0.61; p<0.007). 
  Similarly, out of a possible total 14 points for the HONcode, the average 
  quality score for academic websites (10.91±2.66) was higher compared to 
  private websites (6.44±3.36; p<0.009). The mean consensus reading grade 
  level was similar between academic (11.73±1.68) and private websites 
  (11.78±1.48; p=0.94). Spanish translation was offered by only 7 of the 20 
  websites (5 academic and 2 private websites).
   CONCLUSION: The overall quality and accountability of online content for 
  academic sites was significantly higher compared to private websites. 
  Translation was rarely provided and the readability grade level was 
  significantly higher for both groups than recommended. Improving the 
  quality, accountability, readability, accessibility and incorporating 
  translation in websites can help improve patients' health literacy regarding 
  intravitreal injections, potentially leading to increased adherence to 
  therapy plans and improved treatment outcomes.
  DOI: https://doi.org/10.1016/j.oret.2020.05.019
  URL: http://pubmed.ncbi.nlm.nih.gov/32497854

                                           J Paediatr Child Health. 2020 Jun 01.
12. How adolescent patients search for and appraise online health 
     information: A pilot study.
   McKinnon KA, H Y Caldwell P, Scott KM
  AIM: Adolescents increasingly use smartphones to look up online health 
  information. This pilot study aimed to explore the search and assessment 
  strategies of adolescents looking for online health information.
   METHODS: We performed an observed, practical task on mobile devices, 
  followed by a semi-structured interview with adolescent patients at The 
  Children's Hospital at Westmead, Sydney. Observational data were analysed 
  using an observation rubric, and interviews were transcribed verbatim. Data 
  were analysed through inductive thematic analysis using line-by-line coding 
  and the constant comparative process.
   RESULTS: The research was undertaken with 10 participants. Three themes were 
  identified: (i) participants' searching strategies to find online health 
  information; (ii) techniques for assessing relevance; and (iii) techniques 
  for assessing credibility. These themes demonstrated that most participants 
  accessed online health information due to its ease and accessibility but 
  failed to assess credibility. Most prioritised relevance of information over 
  credibility, determined by their personal knowledge and experience. Our 
  results indicate that there was a large discrepancy between adolescents' 
  ability to search for and assess online health information and their 
  perceived ability. This demonstrates a discrepancy between perceived and 
  performance-based eHealth literacy and highlights poor critical 
  self-awareness, which can prevent adolescents from seeking help. This may 
  underlie the biggest challenge in adolescents' access of online health 
  information and highlights the need for education.
   CONCLUSIONS: Many adolescents' search and appraisal ability is negatively 
  impacted by low eHealth literacy. These adolescents' inability to recognise 
  their need for assistance in improving their search and assessment 
  strategies highlights the need for multi-stage education.
   Keywords: adolescent; digital health literacy; eHealth literacy; health 
    promotion; information seeking behaviour
  DOI: https://doi.org/10.1111/jpc.14918
  URL: http://pubmed.ncbi.nlm.nih.gov/32479676

                                      BMC Public Health. 2020 Jun 05. 20(1): 860
13. Use and importance of different information sources among patients 
     with rare diseases and their relatives over time: a qualitative study.
   Litzkendorf S, Frank M, Babac A, Rosenfeldt D, Schauer F, Hartz T, Graf von 
   der Schulenburg JM
  BACKGROUND: Finding reliable information on one of more than 7000 rare 
  diseases is a major challenge for those affected. Since rare diseases are 
  defined only by the prevalence criterion, a multitude of heterogeneous 
  diseases are included. Common to all, however, are difficulties regarding 
  information access. Even though various quantitative studies have analyzed 
  the use of different information sources for specific rare diseases, little 
  is known about the use of information sources for different rare diseases, 
  how users rate these information sources based on their experiences, and how 
  the use and importance of these information sources change over time.
   METHODS: Fifty-five patients with a variety of rare diseases and 13 close 
  relatives participated in qualitative interviews. For these interviews, a 
  semi-structured guideline was developed, piloted, and revised. Data analysis 
  involved a qualitative content analysis developed by Philipp Mayring.
   RESULTS: The participants considered internet as the most important and 
  widespread information source, especially for early information. Although 
  patients have difficulty dealing with information obtained online, they 
  consider online searching a quick and practical option to gather 
  information. During the course of the disease, personal contact partners, 
  especially self-help associations and specialized doctors, become more 
  important. This is also because information provided online is sometimes 
  insufficiently detailed to answer their information needs, which can be 
  complemented by information from doctors and self-help.
   CONCLUSIONS: People rarely use just one type of source, but rather refer to 
  different sources and informants. The source used depends on the type of 
  information sought as well as other person-related factors such as 
  preexisting knowledge and the disease stage. To improve people's information 
  searching and connect them with medical specialists in rare diseases, a 
  central information portal on rare diseases might be a suitable access point 
  to provide free and quality assured information for patients, caregivers, 
  and physicians. This would allow not only patients but also doctors to find 
  quality assured information on symptoms and therapies as well as patient 
  associations and specialized doctors.
   Keywords: Content analysis; Health information seeking; Informants; 
    Information sources; Online information; Qualitative research; Rare 
    diseases; Self-help; Written information
  DOI: https://doi.org/10.1186/s12889-020-08926-9
  URL: http://pubmed.ncbi.nlm.nih.gov/32503483

                             AMIA Jt Summits Transl Sci Proc. 2020 ;2020 579-588
14. Developing a Search Engine for Precision Medicine.
   Shenoi SJ, Ly V, Soni S, Roberts K
  Precision medicine focuses on developing new treatments based on an 
  individual's genetic, environmental, and lifestyle profile. While this 
  data-driven approach has led to significant advances, retrieving information 
  specific to a patient's condition has proved challenging for oncologists due 
  to the large volume of data. In this paper, we propose the PRecIsion 
  Medicine Robust Oncology Search Engine (PRIMROSE) for cancer patients that 
  retrieves scientific articles and clinical trials based on a patient's 
  condition, genetic profile, age, and gender. Our search engine utilizes 
  Elasticsearch indexes for information storage and retrieval, and we 
  developed a knowledge graph for query expansion in order to improve recall. 
  Additionally, we experimented with machine learning and learning-to-rank 
  components to the search engine and compared the results of the two 
  approaches. Finally, we developed a front-facing ReactJS website and a REST 
  API for connecting with our search engine. The development of this 
  front-facing website allows for easy access to our system by healthcare 
  providers.
  URL: http://pubmed.ncbi.nlm.nih.gov/32477680

                               AMIA Jt Summits Transl Sci Proc. 2020 ;2020 53-62
15. BRret: Retrieval of Brain Research Related Literature.
   Anani M, Kuntz M, Kahanda I
  Research Domain Criteria (RDoC), which is a recently introduced framework 
  for mental illness, utilizes various units of analysis from genetics, neural 
  circuits, etc., for accurate multi-dimensional classification of mental 
  illnesses. Due to the large amount of relevant biomedical research 
  available, automating the process of extracting evidence from the literature 
  to assist with the curation of the RDoC matrix is essential for processing 
  the full breadth of data in an accurate and cost-effective manner. In this 
  work, we formulate the task of information retrieval of brain research 
  literature from general PubMed abstracts. We develop BRret (Brain Research 
  retriever), a novel algorithm for brain research related article retrieval. 
  We use a large dataset of PubMed abstracts annotated with RDoC concepts to 
  demonstrate the effectiveness of BRret. To the best of our knowledge, this 
  is the first study aimed at automated retrieval of brain research related 
  literature.
  URL: http://pubmed.ncbi.nlm.nih.gov/32477623

                             AMIA Jt Summits Transl Sci Proc. 2020 ;2020 561-568
16. Chemical Entity Recognition for MEDLINE Indexing.
   Savery ME, Rogers WJ, Pillai M, Mork JG, Demner-Fushman D
  Chemical entity recognition is essential for indexing scientific literature 
  in the MEDLINE database at the National Library of Medicine. However, the 
  tool currently used to suggest terms for indexing, the Medical Text Indexer, 
  was not originally conceived as a chemical recognition tool. It has instead 
  been adapted to the task via its use of MetaMap and the addition of in-house 
  patterns and rules. In order to develop a tool more suitable for chemical 
  recognition, we have created a collection of 200 MEDLINE titles and 
  abstracts annotated with genes, proteins, inorganic and organic chemicals, 
  as well as other biological molecules. We use this collection to evaluate 
  eleven chemical entity recognition systems, where we seek to identify a tool 
  that effectively recognizes chemical entities for indexing and also performs 
  well on chemical recognition beyond the indexing task. We observe the 
  highest performance with a SciBERT ensemble.
  URL: http://pubmed.ncbi.nlm.nih.gov/32477678

                                   BMC Med Res Methodol. 2020 Jun 01. 20(1): 138
17. Database combinations to retrieve systematic reviews in overviews of 
     reviews: a methodological study.
   Goossen K, Hess S, Lunny C, Pieper D
  BACKGROUND: When conducting an Overviews of Reviews on health-related 
  topics, it is unclear which combination of bibliographic databases authors 
  should use for searching for SRs. Our goal was to determine which databases 
  included the most systematic reviews and identify an optimal database 
  combination for searching systematic reviews.
   METHODS: A set of 86 Overviews of Reviews with 1219 included systematic 
  reviews was extracted from a previous study. Inclusion of the systematic 
  reviews was assessed in MEDLINE, CINAHL, Embase, Epistemonikos, PsycINFO, 
  and TRIP. The mean inclusion rate (% of included systematic reviews) and 
  corresponding 95% confidence interval were calculated for each database 
  individually, as well as for combinations of MEDLINE with each other 
  database and reference checking.
   RESULTS: Inclusion of systematic reviews was higher in MEDLINE than in any 
  other single database (mean inclusion rate 89.7%; 95% confidence interval 
  [89.0-90.3%]). Combined with reference checking, this value increased to 
  93.7% [93.2-94.2%]. The best combination of two databases plus reference 
  checking consisted of MEDLINE and Epistemonikos (99.2% [99.0-99.3%]). 
  Stratification by Health Technology Assessment reports (97.7% [96.5-98.9%]) 
  vs. Cochrane Overviews (100.0%) vs. non-Cochrane Overviews (99.3% 
  [99.1-99.4%]) showed that inclusion was only slightly lower for Health 
  Technology Assessment reports. However, MEDLINE, Epistemonikos, and 
  reference checking remained the best combination. Among the 10/1219 
  systematic reviews not identified by this combination, five were published 
  as websites rather than journals, two were included in CINAHL and Embase, 
  and one was included in the database ERIC.
   CONCLUSIONS: MEDLINE and Epistemonikos, complemented by reference checking 
  of included studies, is the best database combination to identify systematic 
  reviews on health-related topics.
   Keywords: Databases; Overview of reviews; Review methods; Search strategy; 
    Systematic reviews; Umbrella review
  DOI: https://doi.org/10.1186/s12874-020-00983-3
  URL: http://pubmed.ncbi.nlm.nih.gov/32487023

                             AMIA Jt Summits Transl Sci Proc. 2020 ;2020 288-297
18. Text Snippets to Corroborate Medical Relations: An Unsupervised 
     Approach using a Knowledge Graph and Embeddings.
   Kamdar MR, Stanley CE, Carroll M, Wogulis L, Dowling W, Deus HF, 
   Samarasinghe M
  Knowledge graphs have been shown to significantly improve search results. 
  Usually populated by subject matter experts, relations therein need to keep 
  up to date with medical literature in order for search to remain relevant. 
  Dynamically identifying text snippets in literature that confirm or deny 
  knowledge graph triples is increasingly becoming the differentiator between 
  trusted and untrusted medical decision support systems. This work describes 
  our approach to mapping triples to medical text. A medical knowledge graph 
  is used as a source of triples that are used to find matching sentences in 
  reference text. Our unsupervised approach uses phrase embeddings and cosine 
  similarity measures, and boosts candidate text snippets when certain key 
  concepts exist. Using this approach, we can accurately map semantic 
  relations within the medical knowledge graph to text snippets with a 
  precision of 61.4% and recall of 86.3%. This method will be used to develop 
  a novel application in the future to retrieve medical relations and 
  corroborating snippets from medical text given a user query.
  URL: http://pubmed.ncbi.nlm.nih.gov/32477648

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