The MRC Biostatistics Unit is delighted to announce details of a course: Statistical methods for design and analysis of precision medicine trials to be held on 24th - 25th March 2020 in Cambridge, UK.
Precision medicine is about going beyond assessing whether a new treatment works on average to predicting which subgroups of patients receive benefit and to what extent. In this course we introduce the concept of precision medicine and cover innovative approaches to clinical trial design and analysis. This includes novel designs (basket, umbrella, adaptive signature and adaptive enrichment designs) as well as efficient analysis approaches (Bayesian hierarchical modelling and using instrumental variable methods to help estimate sub-group specific treatment effects in the presence of intercurrent events). These approaches have all been developed to improve the power, quality of information, and patient benefit provided by clinical trials. Examples from a wide variety of therapeutic areas will be discussed, with implementation in R software. Perspectives will be given on the future development of design, conduct and analysis of clinical trials in the field.
The intended audience of the course is students and professionals with some knowledge of clinical trials and statistics. Some basic knowledge of R (although full support will be given), knowledge of clinical trials and basic statistics will be helpful. For some parts of the course basic knowledge of Bayesian statistics is assumed.
Course Tutors:
Professor Jack Bowden, University of Exeter
Professor James Wason, MRC Biostatistics Unit and Newcastle University
Professor Christina Yap, Institute of Cancer Research
Dr Haiyan Zheng, Newcastle University
For further information and to register see https://www.mrc-bsu.cam.ac.uk/training/short-courses/statistical-methods-for-design-and-analysis-of-precision-medicine-trials/
The cost of this course is £560 for industry, £440 for academics or public sector and £260 for students.
For answers to course queries, please email [log in to unmask]
This course will run in the same week as our 2 day workshop on Clinical trials in the era of precision medicine: new developments see: https://www.mrc-bsu.cam.ac.uk/news-and-events/workshops/clinical-trials-in-the-era-of-precision-medicine-new-developments/
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