Research Fellow in Computational and statistical analysis of spatial organisation in human eggs. REF (102007-119)
Mathematics Institute, University of Warwick, UK.
Full time, fixed term contract initially for 36 months with possible extension to 60 months, start date ideally before April 2020.
Closing date Dec 4th 2019. Interviews will take place in early December 2019.
Applications are invited for an exciting postdoctoral research fellow position to work on the computational and statistical analysis of chromosome spatial organisation and dynamics in human egg development. Chromosome organisation during egg development is a complex mechanical process that is poorly understood in humans. You will join an interdisciplinary team joint between Warwick and Edinburgh, and undertake the analysis of the imaging data generated on the project, developing bespoke analysis tools utilising a range of computational and statistical methodologies that include multi-target 3D tracking, modelling of object shape (eg mixtures models), optimisation methods, multi-variate analysis and experimental design techniques. The overall aim of the project is to deliver the first comprehensive analysis of chromosome separation during egg development and during early embryonic cell divisions in humans. This project thus has direct relevance to understanding human infertility.
A good background in statistics is desirable as the project will involve developing algorithms incorporating a range of statistical models/tests (mixture models, multiple hypothesis testing), and also involve multivariate modelling and experimental design. Candidates should be able to programme in MatLab (our current tracking software KiT is in MatLab), whilst an ability to programme in Julia, ImageJ, C++ or similar will be an advantage. A willingness and enthusiasm for communicating with biologists is encouraged. A background in biology is NOT required.
If interested please see advert
https://atsv7.wcn.co.uk/search_engine/jobs.cgi?owner=5062452&ownertype=fair&jcode=1842643&vt_template=1457&adminview=1
Applications should be made through the links on this advert.
Scientific queries about the project can be made to Prof Burroughs, [log in to unmask], or see his website https://warwick.ac.uk/fac/cross_fac/zeeman_institute/staffv2/burroughs/.
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