Dear Nianming,
TIV is in CAT12 estimated by using the overall sum of CSF+WM+GM+WMH. If
no WMHs are estimated and WMHs are only internally used for spatial
registration (this is the default), the WMHs are related to GM because
of their similar image intensity.
Best,
Christian
Christian Gaser, Ph.D.
Professor of Computational Neuroscience/Neuroimaging
Biomagnetic Center
Structural Brain Mapping Group
Department of Neurology
Jena University Hospital
Am Klinikum 1, D-07747 Jena, Germany
Tel: ++49-3641-9325778 Fax: ++49-3641-9325772
e-mail: [log in to unmask]
http://www.neuro.uni-jena.de
On 8 May 2019, at 11:00, Nianming wrote:
> Dear Christian,
>
> I have a further question about this topic.
>
> I noticed that source code you posted indicate the TIV = CSF + GM + WM
> + WMH.
> However, in the manual of CAT12, CAT12-Manual.pdf, in page 46, it says
> GM+WM+CSF=TIV.
> So, I am a bit confused whether WM in the CAT12 segmentation includes
> the WMH regions .
> This indeed matters particularly in case of old cohort.
>
> Best regards,
> Nianming Zuo
>
> PhD, Associate Professor
> Brainnetome Center & National Laboratory of Pattern Recognition
> Institute of Automation, Chinese Academy of Sciences
|