Dear All,
I am planning an MR brain imaging study to compare patients with brain tumors of the sellar/parasellar region to matched healthy controls. As it is a rare tumor, we will include a large age range (14-50 years old). In 14 to 20 years old participants in particular there may be still considerable changes in brain anatomy, size, tissue.
For this reason, I just wonder whether it is justified to use the standard adult template for normalization of all participants?
I would very much appreciate any suggestions on this issue.
Best,
Jale
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