Hi Marko,
Thank you very much for this extremely helpful response!
Best,
Jale
Am 18.04.2019 um 08:18 schrieb Marko Wilke:
> Hello,
>
> if you investigate a population spanning a large age range, you will
> always have to compromise. If your sample were large (as in really,
> really large), creating your own template would be an option, but you
> already implied that this is not the case. If you therefore do not
> want to go with the standard template (which I wouldn't either) you
> could look into template creation toolboxes. As it so happens I know
> of one that would span the age range you are interested in and is able
> to create a template matched 1:1 to your input population. You can
> find more details about the CerebroMatic at
> https://www.medizin.uni-tuebingen.de/kinder/en/research/neuroimaging/software/
>
> Note that while you look into this, you might want to download the
> DARTEL dataset as well, as that is usually the next question ;)
>
> Cheers
> Marko
>
> Jale Özyurt schrieb:
>> Dear All,
>>
>> I am planning an MR brain imaging study to compare patients with
>> brain tumors of the sellar/parasellar region to matched healthy
>> controls. As it is a rare tumor, we will include a large age range
>> (14-50 years old). In 14 to 20 years old participants in particular
>> there may be still considerable changes in brain anatomy, size, tissue.
>>
>> For this reason, I just wonder whether it is justified to use the
>> standard adult template for normalization of all participants?
>>
>> I would very much appreciate any suggestions on this issue.
>>
>> Best,
>>
>> Jale
>>
>
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