Hi,
We have performed fMRI scans on 9 rats at two timepoints - baseline and
after rTMS intervention. After performing group ICA, we have run
dual-regression (stage 1 and 2) and then randomise for pair-wise testing
of the intervention effect (by including the .grp file to specify
exchangeability blocks as described in the randomise user guide on
fslwiki). To our surprise, when we set up randomise to do an unpaired
test of the same data, we get much more significant differences than
with the paired setup. We have used the same total number of
permutations for the unpaired and paired setups (512).
Does anyone have an idea how this is possible? Our understanding is that
a paired test should always give more significance than an unpaired test...
Thanks,
Alex
########################################################################
To unsubscribe from the FSL list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=FSL&A=1
|