Dear Rachel,
This will be taken care of automatically by implicitly using this:
https://en.wikipedia.org/wiki/Student%27s_t-test#Equal_or_unequal_sample_sizes,_unequal_variances
Best regards,
Guillaume.
On 05/02/2019 18:32, Rabin, Rachel wrote:
> Hi,
>
>
>
> I have a question regarding a 2x2 model (gender x diagnostic group) I am
> running in SPM. There are 4 groups. The male groups have 2x as many
> participants as the female groups (i.e., 140 versus 70). Is there a way
> to account for this difference in SPM, perhaps by weighing the contrasts???
>
>
>
> Thanks in advance,
>
>
>
> Rachel
>
>
>
> Rachel A. Rabin, PhD
>
> Postdoctoral Fellow
>
> Icahn School of Medicine at Mount Sinai
>
> Friedman Brain Institute
>
> Department of Psychiatry
>
> Neuropsychoimaging of Addiction and Related Conditions (NARC)
>
> 1470 Madison Avenue, 10th Floor 120
>
> 212.824.9328
>
>
>
--
Guillaume Flandin, PhD
Wellcome Centre for Human Neuroimaging
UCL Queen Square Institute of Neurology
London WC1N 3BG
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