This studentship provides stipend and fees for UK/EU applicants together with an integrated transferable skills training programme under the MRC IMPACT scheme: https://more.bham.ac.uk/mrc-impact/
Application deadline is Sunday 20 Jan 2019
Full details are at
https://www2.le.ac.uk/research-degrees/funding/life-sciences/Dudbridge_UOL_MRCIMPACT.pdf
Project Title: New ways to deal with selection bias in genetic studies of disease progression
Project Description: In this project you will develop and apply new statistical methods to identify which genes affect survival time with idiopathic pulmonary fibrosis, and which genes affect growth rates of abdominal aortic aneurysms. The findings will indicate new approaches to treatment and management of these diseases.
Such studies of disease progression can be biased by unknown factors that affect both the risk of developing disease and the course of
disease once established. Our group has recently developed new statistical approaches to correct this bias, using the results of
genome-wide association studies. A substantial part of this project will be evaluating and developing improved methods building on our initial
approaches. This will require programming of statistical analyses and computer simulations, and you should therefore have a demonstrated
aptitude for statistical programming.
You will also analyse large datasets in Leicester and Nottingham on disease progression in idiopathic pulmonary fibrosis and abdominal
aortic aneurysm. You should therefore have an aptitude for working with big data and for presenting results to cross-institutional collaborators
clearly and succinctly.
You will join one of the largest genetic epidemiology groups in the UK, with excellent opportunities for networking and career development in a
fast moving and high profile area.
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