========================================================================================
Design and Analysis of N of 1 Trials
========================================================================================
Tuesday 2nd April 2019 (09:30-16:30 )
Location: Seminar Room, Wellcome Trust Clinical Research Facility, Western General Hospital, Edinburgh
Trainer: Prof Stephen Senn
Course Fee:
* Student Rate: £46 (with a valid matriculation card)
* NHS/Uni Early Bird Rate paid before 5th Feb 2019: £69
* NHS/Uni Rate paid after 5th Feb 2019: £92
If you are looking for an Industry Rate, please contact the Education Core directly on [log in to unmask] or 0131 537 3355
N of 1 trials are trials in which individual patients are repeatedly treated with experimental and control treatments in a deliberate and designed manner using principles of control, randomisation and replication. Their uses include personalising treatment and increasing efficiency by reducing the number of patients it is necessary to study.
In chronic diseases, sets of n-of-1 trials (in which a limited number of patients follow an n-of-1 protocol) have great potential as phase IV trials for understanding components of variation but may also constitute possible Phase III programmes for rare diseases. They can also be used as phase II studies for proof of concept and dose-finding. However, they are often poorly analysed and, indeed, much of the published advice is poor.
This course will present the latest thinking on n-of-1 trials and cover not only their analysis through SAS, R, GenStat and meta-analysis packages but also approaches to design. They will also be critically examined as to their potential use in a) establishing average effects of treatment b) studying the extent to which such effects vary from patient to patient and c) optimising treatment for individual patients.
This course will be given by Professor Stephen Senn, who is well- known for his work on the design and analysis of clinical trials and the application of statistics in drug development.
To book a place, please email the Edinburgh CRF Education Team at [log in to unmask]<mailto:[log in to unmask]> or register online using the following link<https://crts.org.uk/Content.aspx?dbid=crts&layout=CRTS+Master&theme=CRTS&areaid=118&name=Course&iid=4364&type=Content&oid=Screen&uirefid=1272>
Education Core | Wellcome Trust Clinical Research Facility | The University of Edinburgh | Western General Hospital | Crewe Road South | Edinburgh | EH4 2XU
The University of Edinburgh is a charitable body, registered in Scotland, with registration number SC005336.
You may leave the list at any time by sending the command
SIGNOFF allstat
to [log in to unmask], leaving the subject line blank.
The University of Edinburgh is a charitable body, registered in
Scotland, with registration number SC005336.
You may leave the list at any time by sending the command
SIGNOFF allstat
to [log in to unmask], leaving the subject line blank.
|