Hi Katherine.

For patients under 18 years of age, we use the Bedside Schwartz equation. It requires only serum creatinine and patient's height. There is a coefficient, and a variety of slight variations have been suggested, but we use 40 as this seems best aligned to our Roche Enzymatic creatinine. 

EGFR = 40 x (Height in cm / creatinine in micromol/L).

1.Schwartz GJ and Work DF. Measurement and estimation of GFR in children and adolescents. J Am Soc Nephrol. 2009; Nov; 4(11): 1832-643.

2.Schwartz GJ, Munoz A, Schneider MF, et al. New equations to estimate GFR in children with CKD. J Am Soc Nephrol. 2009; 20: 629-637.

3.Staples A, LeBlond R, Watkins S, Wong C, Brandt J. Validation of the revised Schwartz estimating equation in a predominantly non-CKD population. Pediatr Nephrol. 2010 Nov;25(11):2321-6

For oncology our teams sometimes also perform a direct EGFR using 51Cr-EDTA.

Best wishes,

Chris

Dr Chris Chaloner FRCPath
Consultant Paediatric Biochemist and Head of Service Clinical Biochemistry, Oxford Road Campus and Trafford
Department of Clinical Biochemistry,
MFT,
Oxford Road,
Manchester
M13 9WL
UK

T: +44 (0)161 701 2752
E: [log in to unmask] 

www.mft.nhs.uk

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