Dear Chihhao,
Yes, a full factorial design is appropriate here. The contrasts will be
[1 1 -1 -1], [1 -1 1 -1] and [1 -1 -1 1] for the two main effects and
the interaction.
Best regards,
Guillaume.
On 06/08/18 13:56, 連 志浩 wrote:
> Dear experts,
>
>
> I never run 2 x 2 anova with 2nd-level modeling function, so I want to
> make sure that I analysis my data with correct ways.
>
>
> This design has 4 groups (2 x 2, Age: young & old, Genotype: G1 & G2)
> and I have several conXXXX.nii files from each subject with contrast
> Condition A - Condition B.
>
>
> I try to investigate the main effect of Age , the main effect of
> Genotype and the interaction between these two factors.
>
>
> I guess I should use full factorial with Factor "Age" and Factor
> "Genotype" and both have 2 levels, is it right?
>
>
> or using two sample t test is a better way to analysis these effect?
>
>
> Thanks for your reading.
>
>
> Best regards,
>
> Chihhao
>
>
>
--
Guillaume Flandin, PhD
Wellcome Centre for Human Neuroimaging
University College London
12 Queen Square
London WC1N 3BG
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