Hi,
I have a question about the optimization of the imaging parameters. I'm looking for a very small activation in the hippocampus in an event-related fMRi experiment. As a result, detection power is my priority. The event duration is two seconds and ITI is 30 s. As I realized rapid scanning ( TR=2s) reduces the SNR. On the other hand, the TR bigger than event duration may have some negative effects on SNR. I was wondering whether you have some advice about choosing the optimum TR and TE for such an experiment.
Many thanks,
Haleh
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