Dear Moran,
the analysis of FDG data should be similar to fMRI data using CAT12. However, there are two main options: (1) You are interested in using the high-dimensional spatial registration implemented in CAT12 for you FDG data to provide a better overlap of corresponding anatomical regions (voxel-wise approach); (2) You are interested in using the advantages of surface registration and smoothing (surface-based approach).
(1) Voxel-wise approach:
- Co-register T1 to your FDG data
- Run CAT12 with the T1 and save forward deformations
- Apply deformations to FDG data using SPM12 Normalize Write
(2) Surface-based approach:
- Co-register T1 to your FDG data
- Run CAT12 with the T1 and also enable surface processing
- Map unsmoothed FDG data in native space to surfaces using "Map Volume (Native Space) to Individual Surface"
- Resample and Smooth mapped FDG data
Best,
Christian
On Sun, 22 Jul 2018 12:14:00 +0100, Moran Artzi <[log in to unmask]> wrote:
>Hi
>I want to perform vbm analysis (using CAT12) on PET data in order to fined correlations between vector of clinical parameters and brain FDG absorption regions
>What's the best way to test of correlations between brain regions to vector of values (in one group)?
>Should special steps be taken in the analysis of FDG (rather than fmri) data?
>
>Thanks
>Moran
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