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The “Structural Glycovirology” group at Freie Universität Berlin in
Berlin-Dahlem is looking for an enthusiatic postdoctoral scientist with a
strong background in structural biology, holding a PhD in Biochemistry,
Biology or related subjects.
Carbohydrates densely cover every living cell and thus it is not a
surprise that many human viruses interact with carbohydrates as receptors
on their host cells in order to initiate infection. At the same time,
viruses also encounter carbohydrates on their way from one host cell to
another. The specificity and affinity of viral proteins for carbohydrates
determines viral spread, transmission and pathogenesis. We use
glycobiology and biophysics approaches to determine the specificity of
viral proteins for carbohydrates and solve the structures of cognate
protein-carbohydrate complexes by x-ray crystallography. Structural
information is the key to understanding these protein-carbohydrate
recognition processes, which are less well understood than protein-protein
or protein-nucleic acid interactions.
We are looking for
- A strong background in the structure determination of proteins and/or
protein-ligand complexes by x-ray crystallography, NMR or cryo-EM
- Expertise in recombinant protein expression and protein purification –
familiarity with different protein expression systems is helpful
- The candidate should be interested in biochemical and biophysical
approaches to define protein-ligand interactions such as ELISA, FACS, ITC,
SPR, or NMR.
- The candidate should be willing to learn about glycobiology and virology.
- The candidate is expected to be a team player who fits into a
multinational and multidisciplinary research environment.
- Confidence in spoken and written English is a requirement.
We offer
The “Structural Glycovirology” group is a newly established research group
funded by the Emmy Noether Programme of the Deutsche
Forschungsgemeinschaft (DFG). The group is embedded in the Laboratory of
Structural Biochemistry of the Freie Universität Berlin with state of the
art facilities for protein expression and production. The Institute of
Chemistry and Biochemistry is well equipped for x-ray crystallography and
NMR, and is expanding its CryoEM equipment. We also have direct access to
beamlines at BESSY II synchrotron through the Joint Berlin MX Laboratory.
A friendly and multidisciplinary environment provides stimulating grounds
for collaboration with groups in biophysics, cell biology and chemistry.
We offer a full-time position available now until 30 April 2020.
Contact
Please submit your electronic application to me ([log in to unmask])
including a concise description of skills, previous work experiences and
scientific interest until June 25th, 2018. Also provide contact details
for at least two scientific peers who can provide letters of
recommendation.
Looking forward to your response.
With kinds regards,
Ursula Neu
Ursula Neu
Emmy Noether Group Leader
Laboratory of Structural Biochemistry
Freie Universität Berlin
Takustr. 6
14195 Berlin
Germany
phone: +49 30 838 57360
email: [log in to unmask]
http://www.bcp.fu-berlin.de/en/chemie/biochemie/research-groups/wahl-group/mitarbeiter/Dr_-Ursula-Neu.html
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