Dear Víctor,
On Tue, 29 May 2018 19:01:57 +0200, Víctor Costumero Ramos <[log in to unmask]> wrote:
>Dear SPM experts
>
>
>
>I not completely understand what exactly does ROI analysis implemented in
>CAT12 toolbox. I would appreciate some clarification about that.
>
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>
>The description of this analysis provided in Gaser et al., 2016 is as
>follows:
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>"We used maximum probability tissue labels derived from the
>Neuromorphometric atlas (provided by Neuromorphometrics, Inc. (
>http://Neuromorphometrics.com <http://neuromorphometrics.com/>) to estimate
>the sum of local gray matter inside the defined ROI's. The anatomical atlas
>-which is defined in template space - was transformed to native subject
>space using the inverse non-linear deformations needed to spatially
>normalize images to template space."
>
>
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>Does it means that the atlas is transformed to native subject space to
>label each voxel and then the voxel values within each label are summed?
Yes, exactly.
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>If so, what values are used for that sum? Those obtained after segmentation
>(e.g. P1 images)?
The values in native space. For GM these are the p1* images. This is to ensure that data with minimal processing are used for ROI analysis (interpolation, smoothing...).
Best,
Christian
>
>
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>Thanks in advance.
>
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