Dear FSL experts,
I analyzed resting-state fMRI data by ICA-based analysis and have some questions about interpretation of results from dual-regression analysis.
Individual spatial maps are extracted through dual-regression analysis using group ICA maps.
I understand technical process how to calculate beta value in individual spatial map, but what is the physiological meaning/interpretation of beta value?
Here is an example; input group ICA map is DMN, two subject groups (healthy and patients), and group difference after dual-regression analysis and group comparison with GLM (patients > healthy) is at PCC.
Can I intepret that the beta value shows "functional connectivity" between DMN map and a voxel in individual ICA map?
Also, can I say functional connectivity between input DMN map and PCC is higher in patients?
Another questions is, if beta value of PCC is higher, it probably means functional connectivity between the input DMN map and PCC is high.
But what "intra connectivity is high" means?
In addition, is it possible to mention the relation between PCC and other structures which is included in the input DMN map?
I really appreciate it your help.
Best reagards,
Kahori
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