Dear experts,
I am trying to run a longitudinal vertex analysis using FIRST and then randomise. Essentially I have 2 groups (control and cognitive training) and 2 time points (pre post training). I want to see if there is any difference in hippocampal focal atrophy between the 2 groups to see if training reduces atrophy. I am reading around and it seems that the best way to do a repeated measures ANOVA in randomise is calculate the difference using fslmaths and then run a 2-sample t-test on the differences. I have run FIRST on all my data to generate the hippocampal segmentations etc. However, I am struggling to understand where in the pipeline I carry out the sub in fslmaths. I essentially want the diff in bvars but these cant be read into fslmaths or am I missing something?
I really appreciate any help with this.
best wishes
Kathryn
|