On 30/01/2017 23:02, Jan Abendroth wrote:
> I am refining a protein with 16 copies of the same chain per ASU. Fortunately, it is a small
> protein.
>
> Coot has become really slow for this structure. Any real space refinement or placement of a
> water makes coot for 10+ seconds unresponsive. The coot backup files aren't that large,
> around 700k.
> Not displaying NCS and using a small radius for crystallographic symmetry does not help.
>
> I am using a MacBook Pro 2.6GHz i5, 8GB RAM, Intel IRIS 1534 MB, flash hard drive. I has
> never been that slow for 50+ structures.
I've not seen such behaviour.
Possible reasons
1) NFS (slow backups)
2) NCS (matrix updates)
3) symmetry calculation
Paul.
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