Dear all,
I am attempting to run a VBM analysis with child-parent dyads using CAT12/SPM12, and I have some concerns about the normalization approach I should adopt.
I was thinking of the following:
For children (n = 20) - Create a customized Tissue Probability Map using TOM8 toolbox, use low-dimensional SPM12 normalization approach (as suggested in CAT12 manual p. 42)
For adults (n> 50) - Use the SPM12 Tissue Probability Map, use the SPM12's DARTEL template in MNI space
Eventually I would like to correlate the two groups, and I was wondering if the above approach would be ideal, or should I use the SPM12's DARTEL template in MNI space for children for normalization too? I'm aware that I do not have a sufficiently large sample (n > 50) to create a customized DARTEL template for the children.
I would appreciate any suggestions or advice!
Thank you.
Best,
Darren
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