Hello all!
I'm interested in performing cortical thickness analysis (CTA) with FreeSurfer. What are the minimum number of processing steps necessary to do this analysis? i.e. which manual-intervention workflow directive options would you set to give you the minimum information necessary to do CTA?
Below are the options directly copied from Terminal:
Manual-Intervention Workflow Directives:
-autorecon1 : process stages 1-5 (see below)
-autorecon2 : process stages 6-23
after autorecon2, check white surfaces:
a. if wm edit was required, then run -autorecon2-wm
b. if control points added, then run -autorecon2-cp
c. proceed to run -autorecon3
-autorecon2-cp : process stages 12-23 (uses -f w/ mri_normalize, -keep w/ mri_seg)
-autorecon2-wm : process stages 15-23
-autorecon2-inflate1 : 6-18
-autorecon2-perhemi : tess, sm1, inf1, q, fix, sm2, inf2, finalsurf, ribbon
-autorecon3 : process stages 24-34
if edits made to correct pial, then run -autorecon-pial
-hemi ?h : just do lh or rh (default is to do both)
Autorecon Processing Stages (see -autorecon# flags above):
1. Motion Correction and Conform
2. NU (Non-Uniform intensity normalization)
3. Talairach transform computation
4. Intensity Normalization 1
5. Skull Strip
6. EM Register (linear volumetric registration)
7. CA Intensity Normalization
8. CA Non-linear Volumetric Registration
9. Remove neck
10. EM Register, with skull
11. CA Label (Aseg: Volumetric Labeling) and Statistics
12. Intensity Normalization 2 (start here for control points)
13. White matter segmentation
14. Edit WM With ASeg
15. Fill (start here for wm edits)
16. Tessellation (begins per-hemisphere operations)
17. Smooth1
18. Inflate1
19. QSphere
20. Automatic Topology Fixer
21. White Surfs (start here for brain edits for pial surf)
22. Smooth2
23. Inflate2
24. Spherical Mapping
25. Spherical Registration
26. Spherical Registration, Contralater hemisphere
27. Map average curvature to subject
28. Cortical Parcellation (Labeling)
29. Cortical Parcellation Statistics
30. Pial Surfs
31. WM/GM Contrast
32. Cortical Ribbon Mask
33. Cortical Parcellation mapped to ASeg
34 Brodmann and exvio EC labels
Thanks!
Paul
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