Dear all
I have fitted the NAP (NADP) ligand into my model, with the occupancy refined to 0.88. However, the density does not fully cover the entire molecule. Does this happen frequently? How should I model it? In another NCS-related copy, the part of the molecule without density actually clashes with some protein residues.
A small attachment is included.
The crystals were grown in the presence of NADP+. The data extends to 1.9 A.
Thanks.
Mohamed
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