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Overweight/Obesity Linked to Eight More Cancers
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Overweight/Obesity Linked to Eight More Cancers
Zosia Chustecka
August 25, 2016
Medscape
http://www.medscape.com/viewarticle/867919
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Being overweight/obese is already known to increase the risk for certain
cancers, but this association has just become much wider. Another eight
cancers have been added to the list, joining the five already there.
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The new findings come from the International Agency for Research on Cancer
(IARC), which is part of the World Health Organization (WHO). They are
published in the IARC Handbooks of Cancer Prevention, Volume 16: Body
Fatness, which provides an update of part of IARC Handbooks of Cancer
Prevention Volume 6: Weight Control and Physical Activity, published in
2002.
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A summary was published online August 25 in the New England Journal of
Medicine.
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Rather than saying that overweight/obesity increases the risk for cancer,
the IARC has presented its findings another way: "the absence of excess
body fatness reduces the risk of cancers."
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The IARC confirmed its previous findings (published in 2002) for five
cancers ? colorectal, esophageal (adenocarcinoma), renal cell carcinoma,
breast cancer in postmenopausal women, and uterine endometrial cancer.
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Now, from a new evaluation of published scientific literature, the agency
has added eight more cancers to that list: stomach (gastric cardia),
liver, gall bladder, pancreas, ovarian, thyroid, meningioma, and multiple
myeloma.
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There is also limited evidence suggesting a link for three other cancers ?
fatal cancer of the prostate, breast cancer in men, and diffuse large
B-cell lymphoma.
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Several mechanisms linking excess body fat with carcinogenesis were
identified, including chronic inflammation and dysregulation of the
metabolism of sex hormones, the IARC notes.
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The complete article may be read at the URL above.
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Overweight, Obesity, and Mortality in a Large Prospective
Cohort of Persons 50 to 71 Years Old
Kenneth F. Adams, Ph.D., Arthur Schatzkin, M.D., Tamara B. Harris, M.D.,
Victor Kipnis, Ph.D., Traci Mouw, M.P.H., Rachel Ballard-Barbash, M.D.,
Albert Hollenbeck, Ph.D., and Michael F. Leitzmann, M.D.
August 24, 2006 vol. 355 no. 8
http://www.nejm.org/doi/pdf/10.1056/NEJMoa055643
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Sincerely,
David Dillard
Temple University
(215) 204 - 4584
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