I believe the PHYRE2 homology modelling server works by aligning the predicted secondary structure with that of known structures.
Tristan Croll
Lecturer
Faculty of Health
School of Biomedical Sciences
Institute of Health and Biomedical Engineering
Queensland University of Technology
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Kelvin Grove QLD 4059 Australia
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> On 4 Jun 2016, at 2:07 AM, Pedro Matias <[log in to unmask]> wrote:
>
> Dear all,
>
> A colleague is working on a protein for which there is yet no 3D
> structure or a structural homolog. Based on a secondary structure
> prediction only, is it possible to search databases to try and find
> possibly similar proteins (likely with low sequence homology)?
>
> Thanks in advance,
>
> Pedro Matias
>
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