Hi Anderson,
Thank you for the reply. If we want to use TFCE for inference, since VBM and resting state use -T -tfce1D option, TBSS uses -T -tfce2D option, can we run the command like this:
palm -i all_FA_skeletonised.nii -T -tfce1D -i GM_mod_merg_s3.nii -T -tfce1D -i dr_stage2_ic0000.nii -T -tfce2D -i dr_stage2_ic0001.nii -T -tfce2D -i dr_stage2_ic0002.nii -T -tfce2D -d design.mat -t design.con -n 5000 -corrcon -corrmod -save1-p
Or do we have to register every modality to the same space ( standard space, e.g.) and then using the command of NPC:
palm -i all_FA_skeletonised_standard.nii -i GM_mod_merg_s3_standard.nii -i dr_stage2_ic0000_standard.nii -i dr_stage2_ic0001_standard.nii -i dr_stage2_ic0002_standard.nii -d design.mat -t design.con -n 5000 -npc -Tnpc -save1-p
For corrected across, "Each modality will be tested separately", so is it just for estimation of one modality after regressoring out variables of other modalities?
If we want to estimate the interaction between modalities, should we transfer to joint inference (NPC or MANOVA/MANCOVA)? Just like FSLNets, explore the correlation between 2 RSN, using PALM to search the correlation between 2 modalities, for example, change of modality A causing positive/negative alteration of modality B? And estimating the contribution of modality A and modality C to the alteration of modality B?
Moreover, can we use palm to find similar or same changed brain area during modalities, and the link between them:
Modality A shows change in area A (near area B)/ area B, modality B shows change in area B, estimating whether the similar/same change (in spite of the indices for each modality are different) own some relationship.
Is it possible?
Kind regards,
Jian
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