Hello everyone,
It seems CCP4 Blend is routinely used to combine multiple crystal data to amplify anomalous signals when practicing S-SAD.
I'm new to Blend (CCP4 in general) and I was studying Blend in order to carry out my S-SAD experiment, but I'm facing some problems.
I learned that the input for Blend is unmerged .mtz files. I have unmerged .sca files from HKL2000. Is there way to convert .sca to .mtz without merging or loosing information? Or re-processing data with Mosflm or XDS is the only way?
Another question is; does Phenix have equivalent tool to Blend? I learned people use phenix.multi_crystal_average but it doesn't seem to serve the purpose of anomalous signal amplification but it is more about the NCS problems.
Thank you for your attention.
Sincerely,
Sam
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