Hi Gerard,
We had that once, three molecules
4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid bound to our target:
PDB ID 4CLZ
Best
Clemens
> -----Ursprüngliche Nachricht-----
> Von: CCP4 bulletin board [mailto:[log in to unmask]] Im Auftrag von
Joel
> Tyndall
> Gesendet: Dienstag, 12. April 2016 01:51
> An: [log in to unmask]
> Betreff: Re: [ccp4bb] Follow-up to a question from 2002
>
> Hi Gerard,
>
> Indeed I have published one.... 3WNR. A separate structure 3WNT showing
> three similar conformations.
>
> Joel
>
> -----Original Message-----
> From: CCP4 bulletin board [mailto:[log in to unmask]] On Behalf Of
Gerard
> DVD Kleywegt
> Sent: Tuesday, 12 April 2016 6:10 AM
> To: [log in to unmask]
> Subject: [ccp4bb] Follow-up to a question from 2002
>
> Hi all,
>
> In 2002 I asked the BB a question to which I received many useful
responses,
> showing the power of crowd-sourcing (although that term didn't exist yet
at
> the time I think) - http://www.ysbl.york.ac.uk/ccp4bb/2002/msg00887.html
>
> Now I would like to pick the collective CCP4 Bulletin Brain again:
>
> Does any of you know of any examples (available in the PDB) where the same
> ligand is observed in two distinctly different conformations (with
> convincing support in the density) in one and the same structure (i.e.,
same
> PDB entry)?
> This could for example be two copies of a ligand bound to a dimer in
> different poses. I'm interested only in distinct sites, not multiple
> conformations in one site.
>
> I will happily summarise the replies.
>
> Best wishes,
>
> --Gerard
>
> ******************************************************************
> Gerard J. Kleywegt
>
> http://xray.bmc.uu.se/gerard mailto:[log in to unmask]
> ******************************************************************
> The opinions in this message are fictional. Any similarity
> to actual opinions, living or dead, is purely coincidental.
> ******************************************************************
> Little known gastromathematical curiosity: let "z" be the
> radius and "a" the thickness of a pizza. Then the volume
> of that pizza is equal to pi*z*z*a !
> ******************************************************************
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